View MarqMetrix video on Raman data collection and creating a quantitative model and predicting concentration of ethanol using Infometrix software.
Brian Rohrback, president of Infometrix, will join Oliver Steinhof, PAT Scientist at Biogen and Nicolas Langenegger, Senior Associate Scientist at Biogen for this free webinar on September 20, 2021 at 10:00am EST.
Register at: biopharma-asia.com
The increasing use of multivariate models both as part of the control strategy in commercial (bio)pharmaceutical production as well as for process monitoring calls for an efficient strategy for model development and model life cycle management. The traditional approach to develop multivariate models based on spectroscopy involves manual data management such as selection and transfer of spectroscopic data, import into modeling software and selection/exclusion of data. That is followed by addition of reference data, alignment of time stamps and import into the modeling software. 90% of the time required to construct a multivariate model is spent on data preparation. It was decided to develop a solution to automate these steps to prepare (stage) the data required for model development, reducing the time required to prepare a typical set of batch data to about five minutes. A second tool was developed to automatically optimize data pretreatment parameters and spectral range for PLS models. Both tools allow our scientists to invest their time into more value-added activities.
Automating Spectroscopic Calibrations (Slide deck with notes from International Forum for Process Analytical Chemistry meeting in Washington DC, March 4th, 2019. Presented by Infometrix, Inc. and Phillips 66)
A new application note is available on multiple physical property measurements from sensors that were tallied into a single file to create a multivariate profile of the system being measured; a pump in this case. The exercise is to determine when the pump will fail before it fails so that it can be replaced before the failure.
Infometrix now offers Ai-Metrix; its new simplified calibration service to save you time and resources. With efficiency in automation, intelligent data management and speedy calibration, ease burden of maintenance, simplify calibration, and improve model quality. See details on our Ai-Metrix page.